Oat Beta Glucan Powder

The β-(1→3, 1→4) glucan in oats is referred to as oat β-glucan for short, which is a non-starch polysaccharide existing in oat endosperm and aleurone layer cell wall. It is a high molecular polymer formed by connecting monomer β-D-glucopyranose through β-(1→3) and β-(1→4) glycosidic bonds. Among them, the distribution of β-(1→3) and β-(1→4) glycosidic bonds is neither completely ordered nor fully ordered, mainly cellotriose or cellotetraose of β-(1→4) glucan , more than 85% of the oat β-glucan molecules have 1 β-(1→3) glycosidic bond between every 2~3 β-(1→4) glycosidic bonds, and 15% are composed of long chain β-glucans. The (1→4) glycosidic bond is separated by a β-(1→3) glycosidic bond, and its length may be 4, 5 or 8 glucose residues. A straight-chain unbranched polysaccharide structure with β-(1→3) bonds, where the ratio of β-(1→4) to β-(1→3) glycosidic bonds is about 2.4:1. In oat endosperm and aleurone cell wall components, β-glucan accounts for more than 85%. Oat β-glucan is a short-chain glucan with a relatively small molecular weight, and its relative molecular weight ranges from 5300 to 257200.

● Reduce cholesterol
As early as many years, scientists have discovered that bata-glucan can reduce the rate of absorption of fatty acids in the stomach and reduce the synthesis of cholesterol in the human body. With the maturing of bata-glucan research, scholars have successively conducted experiments on animals and humans. A large number of experiments have confirmed that bata-glucan has specific physiological functions in lowering cholesterol and low-density lipoprotein. Scientists have found that the effect of bata-glucan on cholesterol is that it can significantly reduce total cholesterol (TC) and Low-density lipoprotein cholesterol (LDI-TC), while no significant effect on high-density lipoprotein (HDL) and triglyceride (TG). Oat glucan has a significant cholesterol-lowering effect on people with high blood lipids.
There are currently four hypotheses about the mechanism of oat glucan lowering cholesterol:
① It can bind to bile acid, increase the excretion of bile acid, thereby reducing the level of bile acid and plasma cholesterol concentration.
② It can be fermented by microorganisms in the intestine to produce short-chain fatty acids, which can inhibit the synthesis of cholesterol in the liver.
③ can promote the decomposition of LDL-C.
④It can form a high-viscosity environment in the digestive tract, hindering the absorption of fat, cholesterol and bile acid in the digestive tract.
● Hypoglycemic
After eating dextran oat food every day, the blood sugar level of patients can be reduced by about 50%, and the use of oat food can significantly reduce blood sugar At the same time, it has a good repair effect on liver and kidney tissue lesions complicated by diabetes, and can effectively reduce the decomposition of liver glycogen, resulting in lower blood sugar.
● Enhance immunity
Oat glucan has immunoregulatory effects, oat β-glucan can increase the value of mouse lymphocytes, enhance the ability of mice to resist bacterial invasion; it can stimulate mouse peritoneal macrophages to release tumor necrosis factor (TNF-ALPHAhe) and The release of interleukin-1 (In-terlukinIL-1) and macrophage p338DI, after intragastric or parenteral injection of oat dextran, the number of serum immunoglobulins in mice increased significantly, indicating that oat dextran has the ability to improve the immunity of mice. The role of force.
● Anticancer function
The short-chain fatty acids produced by the fermentation of oat glucan in the intestinal tract can reduce the activity of microbial metabolic enzymes such as glucosidase, glucuronidase and urease; the viscous p-glucan can also increase the secondary bile These enzymes and secondary bile acids are the inducing factors of colon cancer, so oat glucan has anti-cancer effects.
● Improve gut
Oat glucan cannot be hydrolyzed in the small intestine, but is degraded in the large intestine and used as a substrate for bacterial fermentation to produce short-chain fatty acids, especially butyric acid, which is beneficial to intestinal function. Oat β-glucan can make mice Bifidobacteria and Lactobacillus increase in intestinal tract and feces, while reducing the number of Escherichia coli, so oat glucan can also improve intestinal function and promote the increase of intestinal beneficial bacteria.
● Beauty effect
People have long known the use of oatmeal to treat dry and itchy skin. The method of use is to make a paste of oatmeal directly on the skin. However, due to the different production methods, the quality of oatmeal is different and the effect is difficult to maintain stability. With the development of science and technology, scientists have gradually discovered the main ingredients and mechanism of action of oatmeal beauty and skin care.
Oat β-glucan has excellent anti-aging effects, can smooth fine wrinkles, improve skin elasticity, and improve skin texture; it has a unique straight-chain molecular structure, which endows good transdermal absorption properties; promotes fibroblasts Synthesize collagen, promote wound healing, repair damaged skin, and give skin a silky moist and smooth touch.

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