CAS 72909-34-3

 

Pyrroloquinoline quinone (PQQ) is a tricyclic ortho-quinone compound and one of the most chemically stable redox cofactors identified to date. Alongside nicotinamide (NAD) and flavin (FAD), PQQ is recognized in biochemical literature as a third-generation redox coenzyme, distinguished by its unusually high resistance to oxidative degradation. Sheerherb supplies PQQ powder produced through both microbial fermentation and chemical synthesis routes, allowing us to match the source method to each buyer's purity, cost, and documentation requirements, and to deliver a consistently high-purity PQQ powder suited for research, nutraceutical, and industrial formulation use.

 

 

Supports Mitochondrial Energy Production

PQQ has been shown to activate a key cell-signaling pathway (SIRT1/PGC-1α) that triggers the body's cells to generate new mitochondria - the structures responsible for producing cellular energy. In practice, this means PQQ works upstream of energy metabolism, rather than simply neutralizing free radicals after the fact. It is one of the more consistently replicated effects of PQQ across published research.

 

Functions as a Natural Redox Cofactor

PQQ acts as a cofactor for certain enzymes, helping them carry out oxidation-reduction reactions - a role similar to that of B-vitamin-derived cofactors like NAD and FAD, but with notably higher chemical stability. This function is what makes PQQ useful not only in biological systems, but also in industrial and research applications involving enzyme-based reactions.

Antimicrobial and Antibiofilm Activity

Newer research has found that PQQ can inhibit the growth of a range of bacteria and fungi, and is particularly effective at suppressing biofilm formation by certain resistant bacterial strains, including MRSA. It works by disrupting bacterial cell membranes and interfering with internal processes the bacteria need to survive. This is a newer, less commercially explored application compared to PQQ's better-known energy-metabolism effects.

 

 

Sheerherb produces PQQ powder through a controlled fermentation-to-crystallization workflow:

Fermentation → Broth Separation → Extraction & Purification → Crystallization → Drying & Micronization → QC Testing

A chemically synthesized route is also available on request for buyers with specific sourcing or documentation preferences.

 

 

We offer white label or private label customization services, including various dosage forms such as capsules, tablets, drops, strips, and gummies, and can be tailored to the customer's product specifications.

 

 

Sheerherb is a PQQ manufacturer and supplier located in China, possessing ISO 9001, ISO 22000, HALAL, organic certification, GMP, and FDA registration. Each batch undergoes independent testing for purity, heavy metals, and microbial safety, providing international buyers with verifiable quality assurance.

We operate our own fermentation and purification facility along with an in-house R&D team, allowing us to maintain batch-to-batch consistency and to support customized purity specifications for buyers with specific formulation requirements - whether you are sourcing PQQ for research use, nutraceutical formulation, or industrial application.

If you wish to purchase PQQ powder in bulk, request a PQQ price quote, or need documentation such as COA and MSDS to evaluate us as a PQQ supplier, our team responds to inquiries within 24 hours. Contact us at chriswang@sheerherb.com to place an order, request a sample, or discuss export logistics.