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Ghk-cu Powder
Product Name: GHK-Cu
Other Name: Glycyl-L-histidyl-L-lysine –copper
Appearence: Blue powder
Cas: 49557-75-7
Formula: C14H24N6O4
particle size: 95% pass through 80 mesh
Grade: Cosmetic grade
Brand: Sheerherb
Shelf Life: 24months
Storage: Cool Dry Place
Description
What Is GHK-Cu?
Copper peptide: It is the ancestor of peptides. Peptides are actually small molecular proteins composed of amino acids. These small molecular proteins are more easily absorbed by the skin. Peptides are made up of some amino acids with a specific sequence connected by amide bonds. Those composed of 2 amino acids are called dipeptides, those composed of 3 amino acids are called tripeptides, and so on. Even if the amino acids are exactly the same, if they are arranged in different ways, they will form peptides with completely different structures. Tripeptide-copper, copper is a trace element needed to maintain body functions (daily requirement 2 mg), has many and complex functions, and is an element needed by various cell enzymes. Because there are many important enzymes in the human body and skin that need Cu ions, these enzymes play a role in connective tissue formation, antioxidant defense, and cellular respiration. Cu ions also perform signaling functions that can affect cellular behavior and metabolism. In the role of skin tissue, it has the functions of anti-oxidation, promoting collagen proliferation, and assisting wound healing.

Certificate Of Analysis
|
Item |
Specification |
Result |
|
Assay |
98% |
98.3% |
|
Physical Control |
||
|
Appearance |
Blue powder |
Conform |
|
Identification |
Conforms with TLC |
Conform |
|
Loss on drying |
≤2.0% |
1.2% |
|
Residue on ignition |
≤5% |
3.2% |
|
Chemical Control |
||
|
Heavy Metal |
NMT 20 ppm |
Conform |
|
Lead |
NMT 3 ppm |
Conform |
|
Cadmium |
NMT 3 ppm |
Conform |
|
Mercury |
NMT 2 ppm |
Conform |
|
Arsenic |
NMT 2 ppm |
Conform |
|
Microbiological Tests |
||
|
Total Plate Count |
NMT 10,000 cfu/mg |
Conform |
|
Yeast & Mold |
NMT 1,000 cfu/mg |
Conform |
|
E. Coli. |
Negative |
Conform |
|
Salmonella |
Negative |
Conform |
|
Staphylococcus |
Negative |
Conform |
|
Packing |
Sealed export grade drum & double of sealed plastic bag. |
|
|
Conclusion |
Product Conforms to Specifications |
|
|
Storage |
Store in cool and dry place, keep away from strong light and heat. |
|
Application of GHK-Cu
1.In the form of skin care products:
GHK-Cu has multiple functions, both as a messenger and as a carrier. Secondly, it has the advantages of mildness, non-irritation, and safety, so it has a high application value in external skin care products.

(1) Anti-aging and anti-wrinkle effects: After the copper peptide enters the skin, it releases signals to induce fibroblasts to become collagen and promote collagen production. At the same time, copper ions are carried into the cell, and copper ions are released after encountering enzymes, and copper ions are very important components in many enzymatic reactions. Researchers have done a lot of research on the anti-aging and anti-wrinkle effects of copper peptides. In vitro experiments have shown that its ability to stimulate the synthesis of collagen precursors is stronger than retinoic acid, vitamin C and other anti-aging ingredients. However, the anti-wrinkle effect is not as fast as that of vitamin A, and it takes several months of continuous use to feel the effect.
(2) Promote healing, repair damaged skin, and improve skin density and toughness: copper peptide can promote the growth, division and differentiation of nerve cells and immune-related cells, effectively promote wound healing and hair growth, and repair damaged skin. For microtrauma, damaged, sensitive and fragile skin on the surface of the skin, products containing copper peptides have a repairing effect.
(3) Antioxidation: The antioxidative effect of blue copper peptide has been confirmed in in vitro experiments and animal experiments. It can block the formation of active oxygen, remove various peroxides, protect keratinocytes from ultraviolet rays, and block free radical damage to the liver to protect the liver. The excellent anti-oxidation effect of blue copper peptide can brighten the complexion, refine the skin and prevent skin aging.
(4) Usage and dosage: Skin Repair Peptide-1 uses copper peptide powder as a product, which can be added in the final stage of cosmetic production. The preparation temperature must be lower than 40°C, and the recommended concentration: 500ppm-2,000ppm.
2. In the form of pharmaceutical preparations or dietary supplements:
GHK-Cu microspheres coated with hydroxypropyl cellulose were used as colon-localized drug release. The release of GHK-Cu was affected by the degree of cross-linking as well as the drug loading, and the microspheres released 50-80% of the drug within 4 hours. These studies suggest that GHK-Cu can be used as a dietary supplement.
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