1. What is it?
Phyllophylline (1,3,7,9-tetramethyluric acid) is a pure alkaloid with a structure similar to caffeine and has an effect similar to that of an adenosine receptor antagonist. Theacrine (TeaCrine) is a natural substance derived from plant extracts traditionally found in the traditional Chinese tea commonly known as Kudingcha.

Because of its unique performance and mood-enhancing properties, theophylline's trademarked compounds like TeaCrine and TeaCor are used in pre-workout nitrogen pump products.

2. What does it do?
Theacrine acts like caffeine, helping to reduce fatigue and dramatically boost energy and physical performance while reducing anxiety. Theacrine works with the body's natural metabolic processes to provide longer-lasting energy, increase mental clarity and improve mood and motivation. the
In particular, theacrine activates dopaminergic receptors D1 and D2, supporting increased production of dopamine, which has been shown to generate more energy, improve mood and provide greater mental focus and clarity. Additionally, theacrine inhibits the production of adenosine, a chemical involved in biochemical processes that promote calmness and relaxation. This results in improved alertness, concentration, physical coordination and cardiovascular and anaerobic performance.

Unlike caffeine, theacrine can significantly boost energy and performance without the severe "burnout" or build-up of tolerance and desensitization over time. Theacrine is a great complement to any pre-workout formula and can be combined with many performance-related ingredients including: caffeine, creatine, protein, amino acids and pre-workout supplements.

Theacrine has also been shown to help maintain inflammation within normal limits and reduce muscle and joint discomfort after strenuous exercise. Theacrine acts as an antioxidant that helps reduce the oxidative stress placed on the body during exercise, as indicated by a reduction in inflammatory markers and a reduction in tissue damage following oral ingestion of theacrine.
3. When to take it?
To take advantage of theacrine's anti-fatigue and performance properties, it is best taken in the morning or 15-30 minutes before exercise. Theophylline powder in pure form can be mixed with water, or mixed with any other type of supplement, and consumed. Pre-workout nitrogen pump supplements containing theacrine should be taken with water before exercise. The most effective dosage is 25 – 50 mg per serving.

4. How long does it take to take effect?
Theacrine starts working as soon as it enters the bloodstream, usually 15 – 30 minutes after consumption. Users can expect to experience a smooth increase in energy, cleansed concentration, and enhanced concentration during this time frame. With consistent use and combined with a sensible diet and exercise regime, you will experience full performance-enhancing effects within the first 2 weeks of use.
TeaCrine vs. Caffeine: The Similarities
You're probably starting to see that there are a lot of similarities between TeaCrine and caffeine. Their molecular structures are very similar, and they both stimulate the central nervous system to boost energy levels.
Both TeaCrine and caffeine may also promote better cognitive function and focus. In addition to increasing work capacity and improving exercise performance, they also offer health benefits, such as improved liver function.
With so many similarities between these two ingredients, you might wonder why people choose to debate which one is best as a pre-workout supplement.
As with many things, the details make or break the difference. There are some notable differences between TeaCrine and caffeine that are worth considering when deciding which pre-workout supplement you want to take.
TeaCrine vs. Caffeine: The Differences

Here are some of the most notable differences between TeaCrine and Caffeine:
Intolerance
Most of us are all too familiar with caffeine tolerance. You know, one scoop of your pre-workout drink used to make you feel ready to overcome any hurdles in your workout, but now you need two or three scoops to get the same effect.
However, TeaCrine does not appear to result in the same degree of tolerance enhancement, and you don't have to keep adding more supplements to get the same benefits you once got.
Relieve pain
Some research suggests that TeaCrine may also help reduce pain.
For example, a 2010 study in mice showed that mice receiving oral TeaCrine experienced pain reduction similar to that provided by the painkiller indomethacin.
In contrast, caffeine has not yet shown any similar analgesic properties.
Stress reliever
For some people, consuming caffeine, especially in high doses, can lead to feelings of anxiety and "jittery". TeaCrine, on the other hand, may actually help reduce stress.
The same mouse study above also showed that mice that received TeaCrine experienced fewer signs of long-term stress, including liver damage, than mice that did not receive any TeaCrine at all.
Smooth, sustained energy
In addition to no tension, TeaCrine also has smoother, longer-lasting energy. TeaCrine gives you longer-lasting energy to get you through your workouts instead of a sudden spike and then crash, and without the feeling you need to take an immediate nap.
That being said, the energy you get from TeaCrine won't last to the point where you won't be able to sleep at night after taking it. As long as you give it time to subside (i.e., you don't let it get too close to your bedtime), you shouldn't experience any insomnia associated with consuming it.
Benefits of Combining TeaCrine and Caffeine
TeaCrine sounds great at first, doesn't it? It certainly has its benefits, but when it comes to pre-workout energy, you don't have to choose between TeaCrine and caffeine. In fact, when you combine TeaCrine and caffeine, you'll see more benefits for your workout than relying on either ingredient alone.
Some of the benefits of enjoying TeaCrine and caffeine togetherinclude:
Better performance and ability to work
When taken alone, both caffeine and TeaCrine can improve your workout performance and ability to work. However, this is an example of an era when two heads were better than one.
When you take a supplement that contains both caffeine and TeaCrine, your workout performance will improve even more significantly for greater gains outside the gym.
More focused
You may find that you can focus better when you take a supplement that combines TeaCrine and caffeine.
Together, these ingredients can provide you with a more powerful focus than either ingredient alone. This will help you stay in shape and continue to push yourself to achieve new goals and surpass your past self.
Longer lasting results
Combined with Caffeine and TeaCrine, you can enjoy longer-lasting energy. This, in turn, helps you get the energy you need without crashing badly at the end of your workout (or, worse, when you're in the middle and really need that extra boost).
No tension
Finally, you'll feel less, if any, jittery when your pre-workout includes TeaCrine and caffeine. You won't experience anxiety or tremors, which, as most of us know, can affect our workout performance. Combine TeaCrine and Caffeine for the best of both worlds.
Get pumped up for your next workout
As you can see, there are benefits to consuming either TeaCrine or caffeine before a workout. You can also enjoy them together for a longer lasting energy boost to help you through tough training sessions without fatigue or burnout.
Are you ready to reap the benefits of one or both of these powerful ingredients? If so, check out our full line of fitness supplement ingredients today. No matter what type of goal you are trying to achieve, we can supply a wide range of effective, high-quality products.






