Theacrine, 1,3,7,9-Tetramethyluric Acid

1. What is 1,3,7,9-Tetramethyluric acid?

Theacrine is an alkaloid that is molecularly similar to caffeine and possesses some unique stimulating properties. Theacrine (TeaCrine) is a natural substance derived from plant extracts traditionally found in traditional Chinese teas commonly known as Kudingcha.

Because of its unique performance and mood-enhancing properties, theophylline's trademarked compounds such as TeaCrine and TeaCor are used in pre-workout nitrogen pump products.

Theophylline (1,3,7,9-tetramethyluric acid) is a purine alkaloid present in the leaves of wild bitter tea (Camellia kucha Hung T. Chang), and its molecular structure is higher than that of coffee commonly found in tea methyl Because of one more (Figure 1). It is precisely because there is one more methyl group than caffeine, matrine has completely different physiological functions and health care effects from caffeine, which has attracted widespread attention from academics and medical scholars.

2. What does it do?

Theacrine acts like caffeine, helping to reduce fatigue and significantly enhance energy and physical performance while reducing anxiety. Theacrine works with the body's natural metabolic processes to provide longer-lasting energy, improve mental clarity and improve mood and motivation.

Theacrine, in particular, activates dopaminergic receptors D1 and D2, supporting increased production of dopamine, which has been shown to produce more energy, improve mood and provide greater mental focus and clarity. Additionally, theacrine inhibits the production of adenosine, a chemical involved in biochemical processes that promote sedation and relaxation. This results in improved wakefulness, concentration, physical coordination, and cardiovascular and anaerobic exercise performance.

Theacrine (1,3,7,9-tetramethyluric acid) is a purine alkaloid found in the leaves of wild bitter tea (Camellia kucha Hung T. Chang), its molecular structure is one more than the common caffeine in tea methyl (Figure 1). It is precisely because there is one more methyl group than caffeine, matrine has physiological functions and health care effects that are completely different from caffeine, which has aroused extensive attention of scholars in the academic and medical fields.

Unlike caffeine, theacrine can significantly enhance energy and performance without severe "weariness" or the build-up of tolerance and desensitization over time. Theacrine is very complementary to any pre-workout formula and can be combined with many performance-related ingredients including: caffeine, creatine, protein, amino acids and pre-workout supplements.

Theacrine has also been shown to help maintain inflammation within the normal range and reduce muscle and joint discomfort after strenuous exercise. Theacrine acts as an antioxidant and helps reduce oxidative stress placed on the body during exercise, as indicated by reductions in inflammatory markers and tissue damage following oral intake of theacrine.

3. When to take it?

To take advantage of theacrine's anti-fatigue and performance properties, it is best taken in the morning or 15-30 minutes before exercise. Pure form of theophylline powder can be mixed with water, or with any other type of supplement, and consumed. Pre-workout nitrogen pump supplements containing theacrine should be taken with water before exercise. The most effective dose is 25 – 50 mg per serving.

4. How long does it take to take effect?

Theacrine starts working as soon as it enters the bloodstream, usually 15 – 30 minutes after consumption. Users can expect to experience a smooth increase in energy, clean focus, and enhanced focus within this time frame. With consistent use, combined with a sensible diet and exercise regime, you will experience full performance-enhancing benefits within the first 2 weeks of use.

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