Panthenol Powder

Panthenol is a derivative of vitamin B5, also known as provitamin B5. Vitamin B5 is pantothenic acid, which is unstable in nature and is easily affected by temperature and formula, which reduces its bioavailability. Therefore, its precursor, Panthenol, is often used in cosmetic formulations. There are three forms of Panthenol: dextrorotary (D-type), levorotatory (L-type) and mixed (DL-type), among which d-panthenol (D-panthenol) has a higher Biologically active, so D-panthenol is mainly used in the cosmetic industry.

1: Moisturizing and improving barrier
The intercellular lipids in the stratum corneum are an important structure for maintaining the skin barrier function. The latest research has found that the intercellular lipids in the stratum corneum of dry skin are arranged differently and are in a rigid environment with poor fluidity. Panthenol itself has the functions of moisture absorption and water retention, while promoting lipid synthesis, increasing the fluidity of lipid molecules and keratin microfilaments, improving the rigid environment between stratum corneum cells, and helping to maintain a healthy skin barrier function.

2: Soothing
The soothing effect of Panthenol mainly comes from two aspects. On the one hand, ubiquinol can protect against oxidative stress damage. Cells will produce active oxygen free radicals under the action of internal and external stress factors. When the ability of cells to scavenge free radicals is insufficient, the accumulated free radicals will have adverse effects on skin health and aging. Ubiquinol can reduce the production of active oxygen free radicals in skin cells, and at the same time up-regulate the skin's own antioxidant mechanism, including inducing skin cells to express more antioxidant factors - heme oxygenase 1 (HO-1), thereby improving The antioxidant capacity of the skin. On the other hand, ubiquinol can reduce the inflammatory response. After capsaicin is used to stimulate keratinocytes, the release of inflammatory factors IL-6 and IL-8 is significantly increased. Reduce inflammation, soothing effect

3: Promote repair
The repair of skin damage is a complex process, mainly including four stages: hemostatic stage, inflammatory stage, proliferative stage and remodeling stage. The establishment and development of in vitro reconstructed skin models provides a convenient platform for evaluating the effects of products or actives on the skin repair process.