Mequinol 4-Methoxyphenol

Mequinol (4-methoxyphenol, CAS 150-76-5), also known as hydroquinone monomethyl ether, is a tyrosinase substrate and competitive inhibitor of melanogenesis. It is the active pharmaceutical ingredient in Solagé, a prescription-only combination product (with tretinoin) approved in the United States for the treatment of solar lentigines (age spots/sun-induced pigmentation).Lekonvia supplies Mequinol API at 99.0%–101.0% assay, produced under GMP conditions with supporting documentation available for regulatory submission.

Related-substance profiles and stability data available on request as part of the technical documentation package.

Mequinol's only established finished-product application is as a prescription pharmaceutical active (in combination with tretinoin), regulated as a drug substance in essentially all major markets. It is not approved for standalone cosmetic use, and safety assessments in some jurisdictions have specifically concluded against its use in unregulated topical products.

Finished Dose Pharmaceutical Manufacturing

Supplied to licensed manufacturers producing prescription combination products for dermatological indications such as solar lentigines, consistent with existing regulatory precedent.

Generic & Branded Drug Development

Used by pharmaceutical companies developing generic equivalents under applicable regulatory pathways (e.g., ANDA, EU generic marketing authorization).

Analytical & Regulatory Reference Use

Supplied in smaller quantities to quality-control laboratories and regulatory bodies requiring a reference standard for compendial testing.

Drug Master File (DMF) or equivalent technical dossier, where applicable to the buyer's jurisdiction
Certificate of Analysis (CoA) per batch, covering assay and related substances
GMP certification and site information for regulatory submission support
Stability data to support shelf-life claims in the buyer's finished product filing

We recommend buyers confirm their own jurisdiction's import/licensing requirements for pharmaceutical APIs, and specifically the regulatory status of mequinol-containing finished products, before placing an order - this varies significantly by country and is more restrictive than for most other actives we supply.

Sheerherb supplies Mequinol API under GMP-certified production, with documentation designed to support licensed pharmaceutical buyers through their own regulatory filings.

For the latest product specifications, documents, or a formal quote, please contact chriswang@sheerherb.com.

packaging and storage
25KG/barrel.
Store in a cool, ventilated and dry place and keep tightly closed. Shelf life is 24 months.