Chlorogenic Acid

Chlorogenic acid is an organic compound, and it is one of the main antibacterial and antiviral effective pharmacological components of honeysuckle and Eucommia. Soluble in ethanol and acetone, very slightly soluble in ethyl acetate.

Chlorogenic acid has a wide range of biological activities. Modern scientific research on the biological activity of chlorogenic acid has penetrated into many fields such as food, health care, medicine and daily chemical industry. Chlorogenic acid is an important biologically active substance, which has the functions of antibacterial, antiviral, increasing white blood cells, protecting liver and gallbladder, antitumor, lowering blood pressure, lowering blood fat, scavenging free radicals and stimulating the central nervous system.

1. Chlorogenic acid helps antibacterial and antiviral
Eucommia chlorogenic acid has strong antibacterial and anti-inflammatory effects, aucubin and its polymers have obvious antibacterial effect, aucubin has inhibitory effect on Gram-negative and positive bacteria. Aucubin has antibacterial and diuretic effects, and can promote wound healing; aucubin and glucoside can also produce obvious antiviral effect after pre-culture, but it does not have antiviral function by itself.
2. Chlorogenic acid can resist oxidation
Chlorogenic acid is an effective phenolic antioxidant, and its antioxidant capacity is stronger than that of caffeic acid, p-hydroxybenzoic acid, ferulic acid, syringic acid, butylated hydroxyanisole (BHA) and tocopherol. The reason why chlorogenic acid has antioxidant effect is because it contains a certain amount of R-OH groups, which can form hydrogen free radicals with antioxidant effect to eliminate the activity of free radicals such as hydroxyl radicals and superoxide anions, thereby protecting Tissues are protected from oxidative damage.

3. Chlorogenic acid can scavenge free radicals, anti-aging, anti-musculoskeletal aging
Chlorogenic acid and its derivatives have a stronger free radical scavenging effect than ascorbic acid, caffeic acid and tocopherol (vitamin E), can effectively scavenge DPPH free radicals, hydroxyl free radicals and superoxide anion free radicals, and can also inhibit low-density Oxidation of lipoproteins. Eucommia chlorogenic acid contains a special ingredient that can promote the synthesis and decomposition of collagen in the skin, bones, and muscles of the human body. It has the functions of promoting metabolism and preventing decline. It can be used to prevent astronauts from bone and muscle damage caused by space weightlessness. At the same time, it was found that the chlorogenic acid of Eucommia ulmoides had obvious anti-free radical effects both in vivo and in vitro.
4. Chlorogenic acid can inhibit mutation and anti-tumor
Modern pharmacological experiments have proved that chlorogenic acid of Eucommia ulmoides has the effect of anti-cancer and tumor suppression. Japanese scholars have studied the mutagenicity inhibitory effect of chlorogenic acid of Eucommia ulmoides, and found that this effect is related to anti-mutogenic components such as chlorogenic acid, revealing that green The importance of ortho acid for tumor prevention.
Polyphenols in vegetables and fruits such as chlorogenic acid and caffeic acid can inhibit the mutagenicity of the carcinogen aflatoxin by inhibiting the activating enzyme; Transport to achieve anti-cancer, anti-cancer effects. Chlorogenic acid has a significant inhibitory effect on colorectal cancer, liver cancer and laryngeal cancer, and is considered to be an effective chemopreventive agent for cancer.
5. Cardiovascular protection
As a free radical scavenger and antioxidant, chlorogenic acid has been proved by a large number of experiments. This biological activity of chlorogenic acid can have a protective effect on the cardiovascular system.

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