Cordyceps polysaccharide is a highly branched galactomannan, which is the most abundant biologically active substance in the ergot fungus Cordyceps sinensis. Its chemical composition mainly includes polysaccharide components and monosaccharide components, with complex advanced components. The special advanced structure makes it have pharmacological effects such as anti-tumor, anti-inflammatory, hypoglycemic, improving organ index, anti-radiation, anti-liver fibrosis, anti-acute and chronic renal failure, especially with the activity of improving immunity. Functional, and has a good pH range, widely used in health food and pharmaceutical industries.

antitumor activity

Many studies at home and abroad have shown that Cordyceps polysaccharides have anti-tumor activity, and most of the anti-tumor effects are indirect killing of cancer cells, that is, by stimulating the body's non-specific defense function, in the case of cancer patients with impaired immunity after radiotherapy and chemotherapy. Combined treatment with radiotherapy and chemotherapy can achieve the purpose of curing the disease. In recent years, through the study of Cordyceps polysaccharide inhibiting tumor genes, reducing the micronucleus rate and inducing tumor cell differentiation, the understanding of the anti-tumor mechanism of Cordyceps polysaccharide not only stops at the inhibition of immune regulation. tumor cell growth.

hypoglycemic effect

There have been many reports on the hypoglycemic activity of artificial Cordyceps sinensis and its polysaccharide extracts, which have significant effects on a variety of diabetic model animals. The main hypoglycemic mechanisms include: stimulating insulin secretion, inhibiting hepatic glucose output, promoting the activity of hepatic glucose metabolism enzymes, and reducing the content of glucose transporters. The hypoglycemic mechanism of Cordyceps polysaccharides is still inconclusive, and the hypoglycemic activities of polysaccharides obtained from different strains and different extraction processes are also significantly different.

protection of the liver

The protective effects of Cordyceps polysaccharide on the liver mainly include protection from chemical liver injury, immune liver injury and liver fibrosis. Most scholars believe that the protective effect of Cordyceps polysaccharide on the liver is mainly through anti-lipid peroxidation, improving human cellular and humoral immune function, and enhancing the phagocytic ability of hepatocytes.

protect kidney function

Studies have found that Cordyceps polysaccharides have protective effects on renal injury caused by various reasons, and can increase renal blood flow, improve renal function, repair renal tubules and correct metabolic disorders.

immune regulation

Cordyceps polysaccharides play a two-way regulatory role on the immune system mainly by activating immune factors and cells and promoting the production of cytokines.

Due to the wide molecular weight distribution range of Cordyceps polysaccharide, excessive molecular weight or too complex spatial structure of polysaccharide will affect the binding of polysaccharide to its specific receptor and reduce the pharmacological activity of Cordyceps polysaccharide. Only polysaccharides with a certain molecular weight range can better play the role of immune regulation. .