Magnesium L-Threonate

 

Magnesium L-Threonate Development

Magnesium is the second most abundant element in human cells, and it affects hundreds of biochemical reactions in the body by regulating enzyme systems.

 

Many friends supplement magnesium in order to improve insomnia, migraine, and relieve stress, but after oral supplementation, magnesium needs to be absorbed through the small intestine and enter the brain, and finally the magnesium content in the brain can be increased to obtain the above benefits.

 

Most of the cheap inorganic magnesium is decomposed into magnesium ions and inorganic salts due to the action of gastric acid. When these decomposed magnesium ions enter the small intestine, it will stimulate small intestinal peristalsis (by affecting intestinal osmotic pressure), resulting in diarrhea, magnesium The example is then excreted with diarrhea rather than being absorbed into the bloodstream by the small intestine.

 

Organic chelated magnesium can avoid the above situation due to its stable structure. They can be absorbed into the blood by the small intestine in a whole form, but facing the blood-brain barrier (the barrier between plasma and cerebrospinal fluid), most of the magnesium is blocked. beyond the barrier.

 

Studies have shown that even if blood magnesium levels are increased by 300%, the changes in cerebrospinal fluid levels are difficult to exceed 19%.

 

Active cellular transport of magnesium ions maintains a higher concentration of magnesium ions in cerebrospinal fluid than in plasma, but also limits the elevation of magnesium ion levels in the brain. That said, in general, only the magnesium left over after the body's magnesium levels are adequate will affect the brain. This is also the reason why magnesium glycinate sleep aids are not as effective as magnesium threonate.

To this end, scientists conducted a lot of screening and testing, and finally locked in magnesium L-threonate: it is the only magnesium supplement that can pass the blood-brain barrier, which means that it can effectively increase the level of magnesium ions in the brain.

 

Iudicium comparans magnesium chloridi, magnesium glycinatum, et magnesium threonatum deprehendi solum magnesium threonatum signanter augeri intentionem magnesii ionum in fluido cerebrospinali.

Magtein[1] Magnesium Brain (L-Magnesium Threonate) coniunctim evoluta est per turmas ab Universitate Tsinghua et MIT a Professore Liu Guosong ducta, physicus notissimus in campo scientiae cerebri globalis inquisitionis.

 

Professor Liu Guosong fuit professor in Department of Brain et Scientiarum Cognitivarum et Donec Biologiae apud Massachusetts Institutum Technologiae, in tenura professoris et praefecti doctoris in Tsinghua Scholae Medicinae Universitatis, Tsinghua University Doctrinae et Memoriae fundavit. Investigationis Centre, et electus est "Tsinghua University" Centum Talents Programma" et "Changjiang Scholarium Professor Illustris".

 

Magna vis notitiarum experimentalium ostendunt magnesium threonatum memoriam emendare posse, praeveniri Alzheimer, sollicitudinem et tristitiam levare, et somnum meliorem fovere synapses neuronales et densitatem in cerebro [2], et comprehendendo meliorem valetudinem cerebri.

 

Cerebrum humanum habet circiter centum miliarda neuronum quae inter se per nexus synapticas communicant et quodlibet neuron milia synapses habet.

Litterae investigationis congruentes divulgatae sunt sicut primo die 28 mensis Ianuarii, anno 2010, mundi prima diaria academica in agro neuroscientiae, Neuron (a sub-aula Cellae). [3]

 

Celeriter magnesii gradus in cerebro boosts, ex sequentibus beneficiis;

 

1. amplio facultatem cognoscitivam (attentio, memoria, doctrina)

 

2. adiuvat reducere frequentiam capitis CROTAPHOS

 

3. Anxietatem et anxietatem insomnia effecerunt, adiuvando modum positiuum (scrotonin formationis sustinendo)

In randomized, geminus-caecus, placebo-continens studium in 2015 [4], 44 participantes (saeculi 50-70 anni) cum leni cognitiva imminutione suppleti sunt cum 2 P. magnesii threonatus cotidie, 3 Proventus post mensem cerebrum eorum ostendit. miscueratque canus per mediocris de 9.4 annis.

 

refer to

1. ^https://magtein.com/pages/science

2. ^ Abumaria N et al. Effects of elevation of brain magnesium on fear conditioning, fear extinction, and synaptic plasticity in the infralimbic prefrontal cortex and lateral amygdala. J Neurosci. 2011 Oct 19;31(42):14871-81. https ://pubmed.ncbi.nlm.nih.gov/22016520/

3. ^Slutsky I et al. Enhancement of learning and memory by elevating brain magnesium. Neuron. 2010 Jan 28;65(2):165-77. https://pubmed.ncbi.nlm.nih.gov/20152124/

4. ^Liu G et al. Efficacy and Safety of MMFS-01, a Synapse Density Enhancer, for Treating Cognitive Impairment in Older Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. J Alzheimers Dis. 2016;49(4 ): 971-90. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927823/

5. ^https://supplementsinreview.com/brand/magtein/

 

 

 

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