Dehydroepiandrosterone Powder

Dehydroepiandrosterone (DHEA) is a steroid hormone naturally produced by the adrenal glands, serving as a precursor in the body's synthesis of both androgens and estrogens. Commercially, DHEA raw material is produced by converting diosgenin - a plant sterol extracted from wild yam (Dioscorea villosa) - into DHEA through a controlled chemical synthesis process, since the human body cannot directly convert dietary diosgenin into DHEA itself.

Sheerherb's DHEA Powder is manufactured under controlled synthesis conditions, with HPLC-verified purity and identity confirmed on every batch. We supply supplement manufacturers and contract manufacturers sourcing DHEA raw material for markets where it is legally permitted for use in dietary supplement formulations - regulatory status varies significantly by country, and we recommend confirming local classification before formulating or importing.

 

Item	Detail
Chemical Name	Dehydroepiandrosterone (Prasterone)
Appearance	White to off-white crystalline powder
Assay	97% / 99% (customizable)
Test Method	HPLC
CAS No.	53-43-0
Molecular Formula	C₁₉H₂₈O₂
Source Process	Synthesized from diosgenin (wild yam-derived plant sterol)
Particle Size	80–100 mesh
Solubility	Insoluble in water; soluble in ethanol and organic solvents
Heavy Metals / Microbial Limits	Meets standard international pharmaceutical/food-grade limits
Shelf Life	24 months when stored properly
Storage	Cool, dry place, protected from moisture and direct light
Certification	ISO 9001, ISO 22000, GMP

Custom purity levels and particle sizes can be arranged for specific formulation needs - request a sample and confirm your local regulatory status before ordering.

 

DHEA Powder is valued mainly for its role as a precursor in the body's natural hormone synthesis pathway, which underpins its functional positioning in markets where it is legally available:

1. Hormone Precursor Positioning

As a direct precursor to androgens and estrogens, DHEA is positioned in formulas targeting general hormonal balance support, particularly in markets addressing age-related decline in natural DHEA levels.

2. Adrenal & Vitality Support Category

Its natural production by the adrenal glands supports its use in vitality and general wellness-positioned formulas.

3. Established Manufacturing Process

Its well-characterized synthesis pathway from diosgenin provides a consistent, analytically verifiable raw material base for formulators.

4. Recognized Ingredient with Long Market History

DHEA has decades of use history in permitted markets, giving formulators a well-documented ingredient to build compliant products around.

4. THE Detailed introduction of production process.

We Dehydroepiandrosterone powder has 2 process routes, one is the dienol ketone route (16DPA), and the other is the 4AD route. The purpose and efficacy of these two processes are basically the same. The difference is that the production raw materials are different, and then the raw materials are produced. costs are different.

Simply put, 16DPA is plant extraction followed by chemical synthesis, and 4AD is phytosterol fermentation followed by chemical synthesis.

In market applications, usually some high-priced products use more 16DPA, while others use more 4AD. In addition to cost reasons, some customers prefer the plant extraction process. It is also possible that most of the raw materials for sterols come from genetically modified soybeans in South America and North America, and the genetically modified factors are rejected by some markets.

 

Dietary Supplements (Where Legally Permitted)

Stable HPLC-verified purity supports capsule and tablet formulations in jurisdictions where DHEA is classified as an allowable dietary supplement ingredient, such as the United States.

Topical & Specialty Formulations

DHEA is also used in topical cream and gel formats in certain regulatory contexts - formulation requirements vary and should be confirmed against local regulations.

Research & Pharmaceutical Applications

Higher-purity grades are used in research settings and, in some jurisdictions, in prescription pharmaceutical formulations.

 

 

Sheerherb has been producing DHEA Powder for years and is certified to ISO 9001, ISO 22000, and GMP standards. As a supplier, we keep pricing competitive without compromising on purity - no unlisted additives, no shortcuts on testing.

Important regulatory note: DHEA's legal status varies significantly by country - it is available as an OTC dietary supplement ingredient in some markets (such as the United States) but is classified as a prescription or controlled substance in many others (including the EU, UK, Canada, and Australia). We supply this raw material for use in jurisdictions where it is legally permitted, and it is the buyer's responsibility to confirm local regulatory compliance before purchase, import, or formulation.

We operate our own production facility and R&D team, which means formulation questions, custom specifications, and sample requests are handled in-house rather than passed through a third party.

If you're sourcing DHEA Powder for a market where it is legally permitted, contact chriswang@sheerherb.com for current pricing, COA samples, and a formal quote - please confirm your target market's regulatory classification when reaching out so we can advise appropriately.