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Reasons for the Decrease of Phosphatidylserine in Human Body

Apr 25, 2022

Phosphatidylserine Raw, also known as complex nervonic acid, is extracted from the residue of natural soybean oil extraction. It is an active substance in cell membranes, especially in brain cells. Its functions are mainly to improve the function of nerve cells, regulate the conduction of nerve impulses, and enhance the memory function of the brain. Because of its strong lipophilicity, it can quickly enter the brain through the blood-brain barrier after absorption, soothe vascular smooth muscle cells, and increase the brain’s brain. blood supply.

The product is a white or light yellow loose powder, which can be emulsified in water. Insoluble in ethanol, methanol; soluble in chloroform, ether, petroleum ether. Synthetic compounds are only soluble in chloroform. Extracts from the bovine brain at room temperature and exposed to air, the daily denaturation is about 0.5%. Natural products (L-α-phosphatidyl-L-serine) are mostly extracted from bovine (sheep) brains or soybean. Due to the difference between R1 and R2, it is a mixture of many compounds.

phosphatidylserine raw materials

Changes in modern eating habits (such as no longer eating offal), increased awareness of eating healthy foods (such as eating low-fat, low-cholesterol foods and avoiding large amounts of meat), and food crises (such as mad cow disease and foot-and-mouth disease) have led people to eat The amount of phosphatidylserine added has been decreasing. More seriously, the content of natural phospholipids in lipid and oil products produced by modern industrialization has decreased, further reducing the daily intake of phosphatidylserine by normal people. In general, if the diet is high in meat and fish, the intake of phosphatidylserine will be about 180 mg/day; if the food is low in fat, the daily intake of phosphatidylserine will be only 100 mg, Even less than 50 mg. According to statistics, the gap between the daily intake of phosphatidylserine and the normal requirement of normal people is between 70-150 mg, and vegetarians are especially lacking, and the gap is 200-250 mg. For these reasons, normal people need 100-300 mg of pure phosphatidylserine daily, and this is even more important for vegetarians, those on a low-fat or low-cholesterol diet, and the elderly. In addition, some other dietary habits can also reduce the amount of phosphatidylserine in the brain. For example, a diet deficient in omega-3 fatty acids reduces the level of phosphatidylserine in the brain by 28%, which in turn alters the biochemical function of the brain's hippocampus.

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